What are the vasoactive drugs?

What are the vasoactive drugs?

Classification of Vasoactive Drugs

  • adrenaline.
  • noradrenaline.
  • dopamine.
  • dobutamine.
  • isoprenaline.
  • dopexamine.

When are vasoactive medications used?

Introduction. Vasoactive medications are indicated when the Systolic Blood Pressure (SBP) has a decrease of > 30mmHg from the baseline or a Mean Arteriole Pressure (MAP) less than 60-65mmHg and when either condition results in end-organ dysfunction due to hypoperfusion.

How do vasoactive drugs work?

A vasoactive substance is an endogenous agent or pharmaceutical drug that has the effect of either increasing or decreasing blood pressure and/or heart rate through its vasoactivity, that is, vascular activity (effect on blood vessels).

What are the 4 vasopressors?

Norepinephrine (Levophed), epinephrine, vasopressin, phenylephrine (Neo-Synephrine), and dopamine are the most commonly used vasopressors for septic shock.

What are inotropic drugs?

Inotropic agents, or inotropes, are medicines that change the force of your heart’s contractions. There are 2 kinds of inotropes: positive inotropes and negative inotropes. Positive inotropes strengthen the force of the heartbeat. Negative inotropes weaken the force of the heartbeat.

What does vasoactive mean?

: affecting the blood vessels especially in respect to the degree of their relaxation or contraction. Other Words from vasoactive Example Sentences Learn More About vasoactive.

Why is vasopressin not titrated?

Vasopressin is not titrated to clinical effect as are other vasopressors and could be thought of more as a replacement therapy and treatment of relative vasopressin deficiency.

Is Nitroglycerin a vasoactive drug?

Nitroglycerin, an organic nitrate, relaxes vascular smooth muscle. However, the dosage of nitroglycerin used clinically results in predominantly venous dilation and preload reduction.

What are examples of vasoactive substances?

Vasoactive agents include histamine, serotonin, bradykinin, angiotensin II, norepinephrine, platelet activating factor, phospholipase A2, arachidonic acid, prostaglandins, glutamate, leukotrienes, free oxygen radicals, the complement-derived polypeptide Csa-desArg, interleukins 1α, 1β and 2, macrophage inflammatory …

What medication is a vasodilator?

List of types and examples of generic and brand name vasodilators

  • benazepril (Lotensin)
  • captopril (Capoten)
  • enalapril (Vasotec, Epaned)
  • fosinopril (Monopril)
  • lisinopril (Prinivil, Zestril)
  • moexipril (Univasc)
  • perindopril (Aceon)
  • quinapril (Accupril)

What are examples of inotropes?

Examples of positive inotropic agents include:

  • Digoxin.
  • Berberine.
  • Calcium.
  • Calcium sensitisers. Levosimendan.
  • Catecholamines. Dopamine. Dobutamine. Dopexamine. Adrenaline (epinephrine) Isoproterenol (isoprenaline)
  • Angiotensin II.
  • Eicosanoids. Prostaglandins.
  • Phosphodiesterase inhibitors. Enoximone. Milrinone. Amrinone. Theophylline.

Is amiodarone inotropic?

In addition to the superior efficacy compared with most other antiarrhythmic drugs, amiodarone has very little negative inotropic activity and a low rate of ventricular proarrhythmia, making it advantageous for use in patients with heart failure [1].

How are vasoactive agents used in critical care?

Vasoactive agents, such as vasopressors and inotropes, are frequently needed to manage the patient in shock and prevent adverse outcomes. This article reviews the clinical manifestations of shock, as well as the vasoactive agents used to manage shock and what critical care nurses need to know about these important drugs.

What do you need to know about vasoactive medications?

Understanding Vasoactive Medications: Focus on Pharmacology… : Journal of Infusion Nursing Not a Subscriber? Separate multiple e-mails with a (;). Thought you might appreciate this item (s) I saw at Journal of Infusion Nursing. Your message has been successfully sent to your colleague. Some error has occurred while processing your request.

When did Journal of Infusion Nursing publish vasoactive medications?

Journal of Infusion Nursing37 (2):82-86, March/April 2014. Separate multiple e-mails with a (;). Thought you might appreciate this item (s) I saw at Journal of Infusion Nursing.

When to use vasopressors in intensive care unit?

An understanding of the pathophysiology of the various types of shock and pharmacology of the pharmacological agents used in the treatment of shock is necessary for intensive care unit clinicians to make appropriate decisions regarding when vasopressors or inotropes are indicated and assess their effectiveness.