Is Theo dur discontinued?

Is Theo dur discontinued?

The Theo-Dur brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

What is theophylline primarily prescribed for?

Theophylline is used to prevent and treat wheezing, shortness of breath, and chest tightness caused by asthma, chronic bronchitis, emphysema, and other lung diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.

Is Theo-24 the same as theophylline?

Theo-24 is the brand name for the 24-hour capsule form of theophylline. The capsule is brand name only, however, the 24-hour tablet form is available as a generic.

What is the pharmacological effect of theophylline?

Mechanism of Action: Theophylline has two distinct actions in the airways of patients with reversible obstruction; smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects).

Is theophylline bad for kidneys?

However, elderly patients may be more sensitive to the effects of theophylline than younger adults, and are more likely to have kidney, liver, heart, or lung problems, which may require caution and an adjustment in the dose for patients receiving theophylline.

Why is theophylline not used?

For maintenance therapy of asthma, theophylline may be obsolete because it is merely a relatively weak bronchodilator that adds little but side effects to dose- optimized inhaled ~2-agents and does not address the underlying inflammation, a fundamental charac- teristic of the disease.

Do doctors still prescribe theophylline?

While theophylline has been used in the treatment of asthma since 1922, it has since fallen in and out of favor with doctors and, today, is not as commonly used as it once was.

Is theophylline still used for COPD?

Theophylline has been used in the treatment of chronic obstructive airway diseases, including chronic obstructive pulmonary disease (COPD), for more than 70 years. It is still widely prescribed worldwide, because it is inexpensive.

Is there a substitute for theophylline?

Abstract: Doxofylline, which differs from theophylline in containing the dioxalane group at position 7, has comparable efficacy to theophylline in the treatment of respiratory diseases, but with an improved tolerability profile and a favorable risk-to-benefit ratio.

What kind of drug is theophylline?

Theophylline is used to treat lung diseases such as asthma and COPD (bronchitis, emphysema). It must be used regularly to prevent wheezing and shortness of breath. This medication belongs to a class of drugs known as xanthines.

What are the side effects of theophylline?

Nausea/vomiting, stomach/abdominal pain, headache, trouble sleeping, diarrhea, irritability, restlessness, nervousness, shaking, or increased urination may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Why is theophylline used for COPD?

Theophylline may have a unique effect in the treatment of COPD by restoring reduced HDAC activity to normal levels, thus suppressing inflammation but also potentially making the patients responsive to corticosteroids.

When to use Theo-Dur in a clinical setting?

In clinical situations where immediate bronchodilatation is required, such as status asthmaticus, Theo-Dur is not suitable. Theophylline has a narrow therapeutic range; the margin of safety above therapeutic doses is small. In patients showing intolerance to theophylline, the therapy should be reassessed.

How long does Theo Dur last in the blood?

Theo-Dur (Theophylline) Once the steady state level has been reached (3 days) the therapeutic blood levels persist for 12 hours in most adult patients. The mean elimination half-life of theophylline in children is about 4 hours and in nonsmoking adults, about 8 hours.

What kind of central nervous system does Theodur have?

Fentadur Central Nervous System Memodrin Pricital Respiratory System Mundisal gel Theodur Gastrointestinal System X-Prep Lanex Urology Prostaplant Dermocosmetics

How old do you have to be to take Theo Dur?

The use of Theo-Dur in children under the age of 6 years is not recommended as a dose schedule in this age group has not been established. Precautions: Theo-Dur tablets should not be chewed or crushed, but may be halved. Marked differences in serum levels may be seen in patients receiving the same theophylline dose.