What is osteocel made of?

What is osteocel made of?

Osteocel is a premier allograft cellular bone matrix designed to mimic the biological profile of autograft. It is comprised of cancellous bone rich in viable cells, combined with demineralized bone matrix from the same donor.

What is a cellular bone matrix?

Cellular bone matrices (CBM) are allograft products that provide three components essential to new bone formation: an osteoconductive scaffold, extracellular growth factors for cell proliferation and differentiation, and viable cells with osteogenic potential.

Where are the viable living cells in osteocel from?

CELLS Osteocel contains viable mesenchymal stem cells. These bone-forming cells are naturally present in our bodies and are essential for bone tissue formation and healing. Osteocel technology preserves the live bone-forming cells in donor tissue.

What is a ViviGen bone graft?

ViviGen is a cellular allograft intended for repair or reconstruction of musculoskeletal defects. ViviGen is being utilized in fusion, nonunion, and malunion for foot/ankle or long bone trauma in patients with compromised biology.

Does ViviGen contain stem cells?

Human bone marrow mesenchymal stem cells (hMSCs, Lonza) were used as a comparative control. Product Description – ViviGen is a HCT/P (Human Cells, Tissues, and Cellular and Tissue-based Product) comprised of cryopreserved, live, viable bone cells within a corticocancellous bone matrix and demineralized bone.

Which is better allograft or autograft?

While autografts have a higher success rate, allografts result in a quicker recovery time. Depending on the injury, your doctor will be able to make the right call for the type of graft to use. A third option is utilizing an artificial graft delivery, such as vibone.

What is the novel component of ViviGen cellular bone matrix?

Vivigen is the first cellular allograft to focus on recovering, processing, and protecting viable lineage committed bone cells. it is comprised of viable cryopreserved corticocancellous bone matrix and demineralized bone.

How does Fibergraft influence cells?

Fibergraft® products utilize proprietary bioactive glass fibers to provide direct cell connectivity, high surface area and optimized resorption rates. FIBERGRAFT® BG Morsels is a purely synthetic bone graft substitute made entirely from crystalline 45S5 bioactive glass.

What is ArthroCell?

ArthroCell is a bone allograft that consists of viable cells called chondrocytes that can generate a new bone cells and thus, help in healing. It is surgically implanted into a person to aid the regeneration of new bone and restore the natural state of the bone.

What kind of cells are in osteocel plus?

Osteocel Plus is an advanced allograft cellular bone matrix that retains its native bone-forming cells, including mesenchymal stem cells (MSCs) and osteoprogenitors. Osteocel is intended for the repair, replacement, and reconstruction of skeletal defects.

Which is bone matrix mimics the biological profile of autograft?

Osteocel is a premier allograft cellular bone matrix designed to mimic the biological profile of autograft. It is comprised of cancellous bone rich in viable cells, combined with demineralized bone matrix from the same donor.

What is the physiologic profile of osteocel 1CC?

Osteocel contains physiologic levels of bone morphogenic proteins (BMPs) 5 from the DBM—no dosing concerns. 1cc of Osteocel has similar numbers of MSCs as 45 cc of unconcentrated BMA in age-matched patients. 6 Osteocel mimics the physiologic profile of autograft.

What kind of tissue does NuVasive use for osteocel?

NuVasive and all establishments that process Osteocel are registered with the FDA and are accredited by AATB. These establishments do not receive donated tissue from outside the U.S. Only tissue recovered by organ procurement organizations, certified by AATB, are used in Osteocel processing.