What is purine derivatives?
What is purine derivatives?
The term “purine derivatives (PD)” refers to allantoin, uric acid, xanthine and hypoxanthine collectively. All four compounds are excreted in the urine of sheep, goat, llamas, red deer and camels; but xanthine and hypoxanthine are virtually absent from urine of cattle, buffaloes and yaks.
Which of the following drugs is purine derivative?
Etofylline nicotinate, a theophylline derivative, is a drug that causes vasodilation and relaxation of smooth muscle….Purine Derivatives.
Drug | Target | Type |
---|---|---|
Pentoxifylline | 5′-nucleotidase | target |
Pentoxifylline | Adenosine receptor A1 | target |
Pentoxifylline | Adenosine receptor A2a | target |
Pentoxifylline | Cytochrome P450 1A2 | enzyme |
What is the purpose of purine?
Purines act as metabolic signals, provide energy, control cell growth, are part of essential coenzymes, contribute to sugar transport and donate phosphate groups in phosphorylation reactions (Jankowski et al., 2005; Handford et al., 2006).
What are the 2 purines?
Nitrogenous bases present in the DNA can be grouped into two categories: purines (Adenine (A) and Guanine (G)), and pyrimidine (Cytosine (C) and Thymine (T)). These nitrogenous bases are attached to C1′ of deoxyribose through a glycosidic bond. Deoxyribose attached to a nitrogenous base is called a nucleoside.
What is difference between purine and pyrimidine?
The purines in DNA are adenine and guanine, the same as in RNA. The pyrimidines in DNA are cytosine and thymine; in RNA, they are cytosine and uracil. Purines are larger than pyrimidines because they have a two-ring structure while pyrimidines only have a single ring.
What is the structure of purine?
Purine is a heterocyclic aromatic organic compound with a chemical formula of C5H4N4. Its chemical structure is comprised of a pyrimidine ring with an imidazole ring fused to it, thus, has two carbon rings and a total of four nitrogen atoms.
What is a purine easy definition?
(PYOOR-een) One of two chemical compounds that cells use to make the building blocks of DNA and RNA. Examples of purines are adenine and guanine. Purines are also found in meat and meat products. They are broken down by the body to form uric acid, which is passed in the urine.
What are the two purines?
Two of the bases, adenine and guanine, are similar in structure and are called purines.
How do you identify purines?
The purines, adenine and thymine, are smaller two-ringed bases, while the pyrimidines, cytosine and uracil, are larger and have a single ring. B. The pyrimidines, cytosine and uracil, are smaller and have a single ring, while the purines, adenine and guanine, are larger and have two rings.
What exactly are purines?
Which is a derivative of the base purine?
2 : a derivative of purine especially : a base (such as adenine or guanine) that is a constituent of DNA or RNA.
How is the word purine used in a sentence?
Definition of purine 1 : a crystalline base C5H4N4 that is the parent of compounds of the uric-acid group 2 : a derivative of purine especially : a base (such as adenine or guanine) that is a constituent of DNA or RNA Examples of purine in a Sentence
What is the name of the white compound purine?
1. a white, crystalline compound, C5H4N4, from which is derived a group of compounds including uric acid, xanthine, and caffeine. 2. one of several purine derivatives, esp. the bases adenine and guanine, which are fundamental constituents of nucleic acids.
How are purine derivatives released from damaged muscle cells?
Purine derivatives released from damaged muscle cells are rapidly converted to uric acid, leading to very high plasma urate concentrations and intrarenal deposition. From: Clinical Biochemistry: Metabolic and Clinical Aspects (Third Edition), 2014