What is the use of airlift bioreactor?

What is the use of airlift bioreactor?

Air-lift bioreactors have been widely used in filamentous fermentation, biological wastewater treatment, production of single cell proteins, and plant and animal cell cultures.

What is an airlift reactor?

Airlift reactors (ALRs) are pneumatically agitated bioreactors where the injection of a gas stream into a specific reactor compartment, the riser, causes the reaction broth to circulate between the riser and an interconnected downcomer compartment containing a smaller (or negligible) gas phase.

What are the advantages of airlift bioreactor over stirred tank bioreactor?

Airlift bioreactors (ALBs) offer advantages over conventional systems, such as simplicity of construction, reduced risk of contamination, and efficient gas-liquid dispersion with low power consumption. ALBs are usually operated under atmospheric pressure.

Why impellers are used in bioreactors?

Why does the bioreactor need an impeller? The primary function of the impeller is to continuously stir the contents of the vessel, ensuring homogenous mixing and therefore providing the cells with consistent access to the nutrients within.

What is the unit of influent flow rate?

2. What is the unit of influent flow rate? where HRT is hydraulic retention time (d) and usually expressed in hours (or sometimes days), the V is the volume of aeration tank or reactor volume (m3), and is the influent flow rate (m3/d).

What is bubble column bioreactor?

A bubble column reactor is an apparatus used to generate and control gas-liquid chemical reactions. It consists of a vertically-arranged cylindrical column filled with liquid, at the bottom of which gas is inserted.

What is difference between impeller and turbine?

An impeller or impellor is a rotor used to increase the pressure and flow of a fluid. It is the opposite of a turbine, which extracts energy from, and reduces the pressure of, a flowing fluid. The work produced by a turbine can be used for generating electrical power when combined with a generator.

Which type of bioreactor is more efficient?

In general, the airlift bioreactors are more efficient than bubble columns, particularly for more denser suspensions of microorganisms. This is mainly because in these bioreactors, the mixing of the contents is better compared to bubble columns.

What are two types of bioreactors?

There are many different types of bioreactors including: stirred-tank, rocker, air lift and fixed-bed. Traditional multiple-use bioreactors require cleaning after each cell culture run. Smaller-scale bioreactors are glass systems and can be sterilized in an autoclave.

What is the unit of flow rate Sanfoundry?

Explanation: Mass flow rate = m/t, => unit = kg/s, volumetric flow rate = V/t, => unit = Liters/s, molar rate = n/t, => unit = moles/s.

Which of the following is unit of flow rate?

The SI unit for flow rate is m3/s, but a number of other units for Q are in common use. For example, the heart of a resting adult pumps blood at a rate of 5.00 liters per minute (L/min). Note that a liter (L) is 1/1000 of a cubic meter or 1000 cubic centimeters (10-3 m3 or 103 cm3).

Which is the best type of bioreactor to use?

The mechanically agitated bioreactors are most commonly used for large-scale culture of plant, animal and microbial cells. In this type of bioreactor, the medium is agitated with the help of a mechanically driven impeller. Various types of impellers are in use, depending upon the requirement.

What kind of bioreactors can airlift reactors be used for?

Airlift reactors have been successfully employed in nearly every kind of bioprocess—bacterial and yeast culture, fermentations of mycelial fungi, animal and plant cell culture, immobilized enzyme and cell biocatalysis, culture of microalgae, and wastewater treatment. FIGURE 5.

How are bioreactors different from mechanical agitation reactors?

These bioreactors are tall and thin as compare to mechanical agitation type reactors. Typically, the height-to-diameter ratio in pneumatically agitated bioreactors is high. In bubble columns, air is bubbled at the base of the column and medium is agitated with this.

How is compressed air used in a bioreactor?

In this reactor compressed air is used for aeration and agitation. Usually the hairy roots require 0.05–0.4 vol of air/vol of liquid/min oxygen supply for optimum growth. In this reactor the aerator is a glass grid which helps to pass the humidified air, which is useful for mixing and oxygenation.